Rohit Arora
PhD, Computational Biology
PUBLICATIONS
New: More publications related to my work at Universite d'Orleans are currently in preparation. They will be cited here upon acceptance/publication!
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Arora R, Di Michele M, Stes E, Vandermarliere E, Martens L, Gevaert K, van Heerde E, Linders JTM, Brehmer D, Jacoby E, Bonnet P. "Structural Investigation of B-Raf Paradox Breaker and Inducer Inhibitors." Journal of medicinal chemistry 58.4 (2015): 1818-1831.
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Di Michele M, Stes E, Vandermarliere E, Arora R, Astorga-Wells J, Vandenbussche J, van Heerde E, ZubarevR, Bonnet P, Linders JTM, Jacoby E, Brehmer D, Martens L, Gevaert K. "Limited proteolysis combined with stable isotope labelling reveals conformational changes in protein (pseudo)kinases upon binding small molecules." submitted to Molecular and Cellular Proteomics.
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Arora R, de Beauchene IC, Polanski J, Laine E and Tchertanov L. "Raltegravir flexibility and its impact on recognition by the HIV‐1 IN targets." Journal of Molecular Recognition 26.9 (2013): 383-401.
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Arora R and Tchertanov L. "The HIV-1 Integrase: Modeling and Beyond " (Chapter Title). An Integrated View of the Molecular Recognition and Toxinology-From Analytical Procedures to Biomedical Applications (Book Title). InTech Publishing. ISBN 980-953-307-586-5.
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Arora R, Tchertanov L. "Structural determinants of Raltegravir specific recognition by the HIV-1Integrase".(2012). JOBIM,ConferenceProceedings.http://jobim2012.inria.fr/jobim_actes_2012_online.pdf
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Mouscadet JF, Arora R, André J, Lambry JC, Delilis O, Malet I, Marcelin AG, Calvez V and Tchertanov L. "HIV‐1 IN alternative molecular recognition of DNA induced by raltegravir resistance mutations." Journal of Molecular Recognition 22.6 (2009): 480-494.
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Ni X, Abdel-Azeim S, Laine E, Arora R, Osemwota O, Marcelin AG, Calvez V, Mouscadet JF and Tchertanov L. "In silico and in vitro comparison of HIV-1 subtypes B and CRF02_AG integrases susceptibility to integrase strand transfer inhibitors."Advances in virology 2012 (2012)
Note: PDFs available on request
ORAL COMMUNICATIONS AND POSTERS
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Poster Presentation "Understanding protein plasticity to improve kinase inhibitor design" at RICT 2014, at Rouen, France (2014)
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Oral Presentation "Understanding protein plasticity to improve kinase inhibitor design" at Journée Fédération ICOA-CBM, at Orléans, France (2014)
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Poster Presentation "A Novel Structure-Based Classification of Protein Kinase Conformations" at Chemical Computing Group - UGM, at Strasbourg (2014)
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Poster presentation “Structural determinants of Raltegravir and their impact on specific recognition by the HIV-1 Integrase” at the Young Researchers in Life Sciences Conference 2012 at Université Paris Diderot, Paris, France (2012)
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Oral Presentation “Structural determinants of Raltegravir specific recognition by the HIV-1 Integrase” at JOBIM-2012, at Rennes, France (2012)
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Oral Presentation “Molecular Dynamics Simulations of the DNA Recognition by the Native and Mutated HIV-1 Integrase” at 4th European Conference on Chemistry for Life Sciences at Eötvös University, Budapest, Hungary (2011).
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Poster presentation “Molecular Dynamics Simulations of the DNA recognition by the Native and Mutated Retrovirus Integrase” at GGMM 2011, La Rochelle, France (2011)
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Poster presentation “In Silico Study of the Resistance Mechanism of Raltegravir, the HIV-1 Integrase Inhibitor” at GTBIO 2009 conference at Institute Pasteur, Paris, France (2009)
AWARDS AND GRANTS
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Winner of the poster prize at RICT 2014
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Obtained a 3 year fellowship for PhD thesis from the French Ministry of Higher Education and Research
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Obtained a full Erasmus Mundus scholarship grant for M.S. in MONABIPHOT (Molecular Nano and Bio Photonics) at ENS Cachan, France and University of Wroclaw, Poland
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Obtained the European Science Foundation (ESF) student grant to attend the 4th European Conference on Chemistry for Life Sciences in Budapest, Hungary
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Winner of the Science Innovation Workshop held at the III International Student Chapters Meeting co-organized with SPIE, OSA and IEEE chapters at Wroclaw University of Technology, Poland
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Received the Semi-Finalist certificate at the Bonn Talent Search Contest Olympiad-2002, New Delhi, India